study on immunity of an experimental oil adjuvant haemorrhagic septicaemia vaccine in cattle.

نویسندگان

a. sotoodehnia

g. moazeni

s. ataei

b. omidi

چکیده

an oil adjuvant vaccine (oav) was prepared from a local strain of pasteurella multocida. strain 6:b was cultured and inactivated by formalin. bacterial pellet was prepared by centrifugation and subsequently adjuvanted by montannide oil isa-70. a dose of prepared vaccine containing 3ml (2mg dry weight/ml) was injected into five calves by im route. animals were bled before and at 24, 90, 150, and 200 days post-vaccination. collected sera were used in passive mouse protection test (pmpt). active mouse protection test (ampt) was carried out for oav according to standard method. results of pmpt showed 100% protection up to 150 days and 66-83% up to 200 days post-vaccination. in ampt, 4 log of protection was gained. in this experiment the immunity induced by oav adjuvanted by isa-70 could protect the calves.

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منابع مشابه

Study on Immunity of an Experimental Oil Adjuvant Haemorrhagic Septicaemia Vaccine in Cattle.

An oil adjuvant vaccine (OAV) was prepared from a local strain of Pasteurella multocida. Strain 6:B was cultured and inactivated by formalin. Bacterial pellet was prepared by centrifugation and subsequently adjuvanted by Montannide oil ISA-70. A dose of prepared vaccine containing 3ml (2mg dry weight/ml) was injected into five calves by IM route. Animals were bled before and at 24, 90, 150, and...

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Haemorrhagic septicaemia in cattle and buffaloes*

Haemorrhagic septicaemia (HS) is a highly fatal disease in cattle and buffaloes, caused by specific serotypes of Pasteurella mul tocida. It is a primary pasteurellosis reproducible in susceptible animals with the specific organism alone. The accepted classification of Pasteurella multocida is based on the identification of its somatic and capsu­ lar antigens. On this basis two serotypes designa...

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عنوان ژورنال:
archives of razi institute

ناشر: razi vaccine & serum research institute (rvsri)

ISSN 0365-3439

دوره 59

شماره 1 2016

میزبانی شده توسط پلتفرم ابری doprax.com

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